Liposomal Bulk Ingredients & Finished Goods
For anyone looking for a trusted liposomal supplement manufacturer, CELLg8® offers high-end liposomal ingredients and finished goods in bulk powders, liquids, and capsules, backed by extensive human clinical studies. Our products are formulated to meet the highest industry standards and are customizable to meet the specific needs of our customers. We are always conducting clinical studies, ensuring that our customers receive the highest quality products. Our clients may also leverage our studies to enhance their authority (no co-branding required!) in an ever-competitive market. Trust CELLg8® to deliver the supplements your business needs to succeed!
Featured Clinical Study
Liposomal Vitamin C
When taking 4g of regular Vitamin C versus 4g of Liposomal Vitamin C, the liposomal form delivered higher levels of Vitamin C to the bloodstream. This led to a reduction in oxidative stress, even during stressful situations. The newest version of Liposomal Vitamin C (CELLg8®) has a small particle size with 92% of the particles being tightly controlled in size, showing the consistent quality of the product.
- Vitamin C Study
- Green Tea Study
- Glutathione Study
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Vitamin C
When taking 4g of regular Vitamin C versus 4g of Liposomal Vitamin C, the liposomal form delivered higher levels of Vitamin C to the bloodstream. This led to a reduction in oxidative stress, even during stressful situations. The newest version of Liposomal Vitamin C (CELLg8®) has a small particle size with 92% of the particles being tightly controlled in size, showing the consistent quality of the product.
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Green Tea
A study was done with 26 people to compare the effectiveness of a green tea extract found in CELLg8® Green Tea compared to a regular green tea extract found in other supplements. The study was not randomized and the participants didn't know which extract they were taking. They took 200mg of a regular green tea extract twice a day, then had a 14-day break, and then took 200mg of the CELLg8® extract twice a day. Blood samples were taken 24 hours after each consumption to measure the amount of catechin, an important component of green tea, in their blood.
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Glutathione
A study was done to see if a special liposomal form of glutathione, which is found in CELLg8® glutathione, could increase levels of glutathione in the blood and help with detoxification. Seven people took a regular glutathione powder, then after a week's break took the CELLg8® liposomal glutathione liquid. The results showed that the liposomal form increased blood levels of glutathione by 22%, while the regular powder did not change levels. In another study, four people took 750 mg of CELLg8® glutathione twice a day for 30 days. This led to improved liver function and detoxification as shown by a decrease in bilirubin and a 39% decrease in mercury.
Liposomal Mineral Absorption
IRON
In a randomized crossover trial, 25 healthy participants ingested either a liposomal multivitamin/mineral or a non-liposomal multivitamin/mineral product. Blood analyses for iron and magnesium were conducted at baseline and every two hours for six hours. Iron levels were significantly increased in the liposomal multi compared with the non-liposomal. Magnesium levels were not significantly different (possible due to the low amount of magnesium in each product). The researchers’ conclusion was that iron absorption from the liposomal multi is significantly enhanced by the liposomal delivery technology.
CELLg8®
Green Tea
A single centre, non-randomised, blind crossover study involving 26 participants . The purpose of the study was to assess the bio-availability of the green tea extract used in the production of CELLg8® Green Tea compared to a standard commercially available extract of green tea commonly found in green tea supplements. Participants consumed 200mg twice per day of a standard green tea extract followed by a 14-day washout period and thereafter 200mg twice per day dose of the extract found in CELLg8® Green Tea was consumed. Blood samples were drawn over a 24-hour period post-consumption to measure levels of catechin concentrations in the blood.
A Pilot Study
Glutathione
A clinical study was undertaken to assess the effect of liposomal glutathione on blood levels and detoxification processes. Seven individuals took a standard glutathione powder, then after a one-week washout took a liposomal glutathione liquid (CELLg8®). Peak blood glutathione was compared, with the liposomal preparation resulting in 22% increase in glutathione levels while the standard glutathione did not change blood glutathione levels.. In another small, open-label study, four healthy individuals took 750 mg of CELLg8®glutathione twice daily for 30 days. Improved detoxification and liver function was demonstrated by decreased bilirubin and 39% decreased mercury.
- B12
- Curcumin
- EGCG
- Iron
- Ketones
- Sleep
- Vitamin D
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Vitamin B12
A study was done with six people to compare the effects of two different forms of vitamin B12 - a liquid form and a capsule form. Each person was given 3 mg of vitamin B12 in one form, waited 14 days, and then took the other form. Almost all the people had higher levels of vitamin B12 in their blood after taking the capsule form compared to the liquid form. The average increase was six times more after taking the capsule form.
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Curcumin
The efficacy of higher doses (0.5 mg and 1 mg) of Liposomal Curcumin was found to be better than the 0.25 mg dose in improving metabolic function in subjects with metabolic slowdown. The study followed strict protocols and considered subjects individually to ensure clinical translational efficacy. The results suggest that Liposomal Curcumin can effectively rebound metabolic function.
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EGCG
EGCG is a type of plant compound called a catechin. Catechins are part of a larger group of compounds called polyphenols. EGCG and other catechins protect cells from damage caused by harmful particles called free radicals. Eating foods high in catechins can help reduce damage from free radicals.
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Iron
A study was done with 25 healthy people who took either a multivitamin/mineral supplement in a special form called liposomal or a regular multivitamin/mineral supplement. Their blood was tested for iron and magnesium levels at the start and every two hours for six hours. The results showed that iron levels were higher in people who took the liposomal supplement compared to the regular one. However, magnesium levels were not different between the two groups. The researchers found that the special liposomal form helped the body absorb iron better.
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Ketones
In a study, participants took a one-time 5-gram dose of a liposomal ketone product. Blood ketones were measured before and after taking the product, and the results showed a significant increase in blood ketones starting 15 minutes after ingestion. The highest increase was seen at 30 minutes, with an average level of 214% over the baseline. The blood ketones stayed above the baseline level for over two hours. The study suggests that liposomal ketones are quickly absorbed into the bloodstream and provide the benefits of a ketogenic diet without dietary restrictions.
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Sleep
The results of this study of postmenopausal women indicate that CELLg8® SLEEP significantly improves sleep duration and decreases the number of awakenings, compared to placebo. While the results of the sleep duration were varied, the majority of subjects reported a decrease in the number of times awakened during the night. The study also suggests that chronic pain may have affected the results of the study. Additionally, 75% of the subjects preferred the SLEEP product over the placebo.
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Vitamin D
15 healthy people were tested for their Vitamin D levels, then took a liposomal product with 125 mcg Vitamin D and 400 mcg Vitamin K for 30 days. On average, their Vitamin D levels increased by 73%, compared to a 16% average increase from non-liposomal Vitamin D supplementation. The increase was even greater for those who started with low Vitamin D levels, with an average increase of 112% in the liposomal vitamin D group.
The study shows that taking liposomal Vitamin D leads to better Vitamin D absorption, resulting in higher levels compared to traditional non-liposomal Vitamin D supplementation.
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Vitamin B12
A study was done with six people to compare the effects of two different forms of vitamin B12 - a liquid form and a capsule form. Each person was given 3 mg of vitamin B12 in one form, waited 14 days, and then took the other form. Almost all the people had higher levels of vitamin B12 in their blood after taking the capsule form compared to the liquid form. The average increase was six times more after taking the capsule form.
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Iron
A study was done with 25 healthy people who took either a multivitamin/mineral supplement in a special form called liposomal or a regular multivitamin/mineral supplement. Their blood was tested for iron and magnesium levels at the start and every two hours for six hours. The results showed that iron levels were higher in people who took the liposomal supplement compared to the regular one. However, magnesium levels were not different between the two groups. The researchers found that the special liposomal form helped the body absorb iron better.
CELLg8® Powered
EGCG
EGCG is a type of plant compound called a catechin. Catechins are part of a larger group of compounds called polyphenols. EGCG and other catechins protect cells from damage caused by harmful particles called free radicals. Eating foods high in catechins can help reduce damage from free radicals.
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Ketones
In a study, participants took a one-time 5-gram dose of a liposomal ketone product. Blood ketones were measured before and after taking the product, and the results showed a significant increase in blood ketones starting 15 minutes after ingestion. The highest increase was seen at 30 minutes, with an average level of 214% over the baseline. The blood ketones stayed above the baseline level for over two hours. The study suggests that liposomal ketones are quickly absorbed into the bloodstream and provide the benefits of a ketogenic diet without dietary restrictions.
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Vitamin D
15 healthy people were tested for their Vitamin D levels, then took a liposomal product with 125 mcg Vitamin D and 400 mcg Vitamin K for 30 days. On average, their Vitamin D levels increased by 73%, compared to a 16% average increase from non-liposomal Vitamin D supplementation. The increase was even greater for those who started with low Vitamin D levels, with an average increase of 112% in the liposomal vitamin D group.
The study shows that taking liposomal Vitamin D leads to better Vitamin D absorption, resulting in higher levels compared to traditional non-liposomal Vitamin D supplementation.
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Curcumin
The efficacy of higher doses (0.5 mg and 1 mg) of Liposomal Curcumin was found to be better than the 0.25 mg dose in improving metabolic function in subjects with metabolic slowdown. The study followed strict protocols and considered subjects individually to ensure clinical translational efficacy. The results suggest that Liposomal Curcumin can effectively rebound metabolic function.
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Sleep
The results of this study of postmenopausal women indicate that CELLg8® SLEEP significantly improves sleep duration and decreases the number of awakenings, compared to placebo. While the results of the sleep duration were varied, the majority of subjects reported a decrease in the number of times awakened during the night. The study also suggests that chronic pain may have affected the results of the study. Additionally, 75% of the subjects preferred the SLEEP product over the placebo.
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Vitamin B12 Study
A single-dose, crossover study was conducted in six human subjects of equivalent doses of two dosage forms of vitamin B12 – a standard liposomal liquid and a liposomal powder-filled capsule (using CELLg8® technology). Each subject was given 3 mg of CELLb12® in one dosage form, followed by a washout period of 14 days, then dosing with the other dosage form.
All subjects (with one exception) had an increase above baseline at one or more time points over 135 minutes. Serum B12 increased six-fold on average after taking the CELLb12® liposomal capsule compared to the traditional liposomal liquid when comparing the highest peak of each subject’s serum B12.
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Vitamin C Study
When comparing a “normal” Vitamin C ingestion (dose of 4g) to a Liposomal Vitamin C (also 4g), it’s evident that our CELLg8® Liposomal Delivery System provides much greater circulating Vitamin C concentrations. With increased efficacy, oxidative stress was reduced even during the increased oxidative stress of reperfusion, resulting in meaningful Vitamin C concentration. As CELLg8® has entered the 8th and final generation, our Liposomal Vitamin C had a peak particle size of 8nm, with 92% of the particles being between 60 and 172nm. This tight distribution is indicative of the reproducible and highly controlled manufacturing methodology of CELLg8® Liposomes.
CELLg8®
EGCG
Referred to as epigallocatechin gallate, EGCG is a catechin, which is a kind of plant-based compound. Catechins are further classified into a bigger group of plant compounds known as polyphenols. EGCG and other relevant catechins can protect against cellular destruction brought about by free radicals. Such particles are formed in the body and can harm cells when their numbers soar too high. Eating foods that are rich in catechins can help limit the damage caused by free radicals.
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Ketones Study
Change in Blood Ketones After Single-Dose Supplementation with Liposomal Ketone Formulation
Protocol: Participants ingested a one-time 5-gram dose of a 50:50 liposomal preparation of ketone monoester/1,3-butanediol.
Laboratory Analyses: Baseline blood ketone measurement using a ketone meter (KetoCoach meter), then measurements at 15 minutes post-ingestion, 30 minutes post-ingestion, 60 minutes post-ingestion, and a final measurement at 120 minutes.
Results: Fifteen minutes after ingesting the liposomal ketone product, all participants had an increase in blood ketones, ranging from 120% to 250% of the baseline level (avg 174%). At 30 minutes post-ingestion, participants’ blood ketones increased from baseline an average of 214%. At 60 minutes, a 66% increase over baseline was seen, and at 120 minutes a 43% increase over baseline was seen. Participants also noted increased mental clarity and acuity.
Conclusions: Liposomal ketones are quickly absorbed into the bloodstream, shown by the average level of 174% over baseline at 15 minutes. This continued at 30 minutes when the greatest increase over baseline was seen – an average level of 214%. Blood ketones stayed at levels above baseline at 60 and 120 minutes. This study shows that ingestion of a liposomal ketone product significantly increases blood ketones starting at 15 minutes and continuing for over two hours. With the peak in blood ketones at 30 minutes, it is advisable to ingest this product 15-30 minutes prior to a workout, to maximize energy and workout strength. Exogenous ketones can serve as an alternate energy source that reduces carbohydrate and protein metabolism, while also decreasing fat storage. Ketogenic diets are commonly used to enhance weight loss, mental clarity, exercise performance, and recovery; however, they are cumbersome and difficult for many people to continue long-term due to dietary constraints. Exogenous ketones offer a method of increasing blood ketones quickly without dietary restrictions and may offer a less complicated approach to obtaining the health benefits of ketosis.
Summary
- Ketosis in 20 minutes
- Increased mental clarity and sharpness
- Mimics benefits of intermittent fasting
- Provides effects of a ketogenic diet without the hassle
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Vitamin D Study
The Effect of a Liposomal Cholecalciferol Preparation on 25(OH) Vitamin D Levels – A comparative, open-label study
Fifteen healthy participants underwent baseline 25(OH) Vitamin D testing, followed by supplementation with a liposomal product containing 125 mcg (5,000 IU) vitamin D and 400 mcg vitamin K (as MK7) daily for 30 days. Participants in this study had an average increase in serum 25(OH) Vitamin D of 73% over baseline. (Fig 1) For comparison, the average increase in 25(OH) Vitamin D with supplementation of a non-liposomal preparation for 30 days at this dosage is 16%.
Individuals who began the study with a 25(OH) Vitamin D level in the “insufficient” range (below 30 ng/mL) had an even greater response, averaging a 112% increase. (Fig 2)
Conclusion: Supplementation with a liposomal vitamin D product for 30 days resulted in a much greater increase in serum 25(OH) Vitamin D than typical results after supplementation with a non-liposomal preparation (avg 73% vs 16%), proving the superior absorption of liposomal Vitamin D.
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Curcumin Study
Three different doses of Liposomal Curcumin were given orally to subjects after metabolic onset. The efficacy of two high doses(0.5mg and 1mg) is obviously better than the 0.25mg dose.
The metabolic function study protocol
- We have much stricter standards when performing efficacy studies:
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- Other studies treat subjects as a group despite not all having metabolic slowdown
- We consider subjects individually (only subjects with metabolic slowdown were included)
- Our goal is to make sure the efficacy could be clinically translational
- Below is the second study we have performed with Liposomal Curcumin
Conclusion
- Liposomal Curcumin was shown to rebound metabolic function in subjects.
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Sleep Study
CELLg8® Sleep is designed to reduce the time it takes to fall asleep, lengthen the duration of sleep, and provide renewed vitality after waking up in the morning, with only half of the recommended dosage of a standard supplement. This can also result in fewer instances of waking up during the night.
DESIGN:
8 Participants
Single-blind study comparing CELLg8® SLEEP product vs. placebo
Each participant took one product for 7 days, then crossed over to the other product
RESULTS:
Placebo did not improve sleep in any subject
When taking the SLEEP product, duration of sleep increased in 50 percent (n=4) by an average of 9-percent., decreased in 37 percent (n=3), and stayed the same in one.
Three of the four who felt no difference between the two products were experiencing chronic pain (none of the other subjects had chronic pain), which may have confounded the results.
Seventy-five percent of subjects in the treatment group had a significant decrease in the number of times awakened, averaging a 50-percent improvement in awakenings.
Seventy-five percent of subjects preferred the SLEEP product over the placebo.
Understanding CELLg8® Liposomes
CELLg8® is a pioneer in liposomal technology, having honed its expertise over the past two decades. Our liposomal delivery system has undergone 8 generations of development, leading to the current and most advanced iteration, CELLg8® Liposomes. Clinical studies have shown that our liposomes result in better absorption, enhanced efficacy, and zero side effects. Our commitment to continuous research is evident in the multiple ongoing studies aimed at further establishing the effectiveness and safety of CELLg8® technology.
CELLg8® Liposomal Supplement Manufacturing Solutions
CELLg8® - Your One-Stop Shop for Liposomal Supplement Manufacturing Solutions We offer a comprehensive B2B ingredient sourcing and manufacturing service for custom and white-labeled liposomal vitamins, minerals, and herbal supplements. Choose from a variety of packaging options including bottles, mist sprays, squeezable bottles, capsules, softgels, and bulk powders to best meet your needs and those of your customers.
- Liquids
- Bulk Powders
- Capsules & Softgels
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Liquids Manufacturing
At CELLg8®, we are experts in the formulation of liquid liposomal supplements. With years of experience and thousands of successful formulations under our belt, we have a proven track record of delivering high-quality, great-tasting supplements. Whether it's a custom flavor or a specific consistency you're after, we understand the importance of getting these details right. That's why we take the time to carefully craft each and every formula, ensuring that your customers will love the taste, smell, and feel of your supplement.
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Bulk Powders Manufacturing
Looking for top-quality CELLg8® Bulk Powders that are backed by clinical studies? Look no further! Our stock includes a wide variety of options, all conveniently packaged in 25 kg boxes. And if you're looking for something more personalized, our team of doctors can work with you to create a custom formula tailored to your unique needs. Trust in the power of CELLg8® Bulk Powders for all your supplement needs.
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Capsules & Softgels Manufacturing
Capsules and softgels are widely favored packaging options for CELLg8® products due to their versatility and convenience. These formats can accommodate both powders and liquids, making them suitable for a wide range of formulations. This flexibility allows CELLg8® to offer its customers a variety of delivery options that cater to their specific needs and preferences. Whether they prefer a quick-release powder or a longer-acting liquid, CELLg8® can provide them with a product that meets their requirements. This versatility also allows CELLg8® to adapt to new product trends and advancements in the industry, making it possible for the company to stay ahead of the competition. Overall, the popularity of capsules and softgels as packaging options for CELLg8® products speaks to their effectiveness and ease of use.
CELLg8® Research
Understanding CELLg8® Liposomes
CELLg8® has developed industry-leading liposomal technology over the last 20+ years. At this time, CELLg8® has been through 8 generations and is now in its final iteration. CELLg8® Liposomes have been clinically proven to have better absorption, increased efficacy, and no side effects. We currently have multiple ongoing studies to further prove the effectiveness and safety of CELLg8® Technology.
Stomachs will vaporize more nutrients than they absorb. Humans are only able to absorb a tiny percentage (typically 1-5%) of nutrients in vitamins and other ingredients. When these ingredients are encapsulated within liposomes, our bodies can absorb up to 15 times more nutrients because we won’t reject the liposomes. Liposomes are the future of supplements.
Science has our back
From the founding of our company, we have always made it a goal to provide proof to our clients and consumers that the products we make don't just work incredibly well, they are also very safe to use. At CELLg8®, we use significant resources in researching, conducting, and publishing clinical studies to prove the efficacy of our technology.
Liposome Manufacturing
Our process from start to finish is gentle on the ingredients to optimize shelf life. We don't use heat, pressure, or chemicals to produce CELLg8® liposomes.
CELLg8® is scaleable
CELLg8® Liposomes can be produced at an industry leading rate, allowing for mass production on multiple products. Our manufacturing facilities are able to produce from 10,000 to 50,000 bottles as finished products per day. We can also produce over 10,000 kg of bulk material per day.
- Effective
- Non-Sticky
- Stable for 2-3 Years
Bulk CELLg8® Powders
Clinically backed with published studies!
Choose from a wide array of stock in 25 kg boxes or create your own custom formulas with our doctors.
CEllg8® Liquids
Finished Goods or Bulk - We carry a wide variety of stock, ready to sell products for white label of or create your own custom products with custom packaging and formulas.
CELLg8® Capsules & Softgels
Choose from a wide array of stock capsules ready to sell on a store shelf or create your own custom formulas with custom packaging of your choice.
Melatonin
N-Acetylcysteine
Resveratrol
Rhodiola Rosea
Shiitake Mushroom
Zeaxanthin
Phosphatidylcholine
Linoleic Acid
Oleic Acid
Vitamin B Series
Vitamin C Series
Vitamin D
Vitamin K
Chromium
Selenium
Acai Berry
Astaxanthin
Astragalus
Bacopa
Curcumin
GABA
Ginger Root
Ginkgo
Glutathione
Green Tea
Guarana
Hesperidin
Huperzine A
Maca Root
See a CELLg8® Liposome in Action
Transmission Electron Microscope
See CELLg8 liposomes pictured under a TEM to the left. Here you can see the full encapsulation of the nutrient within the liposome. When viewing a liposome under a TEM, it's important that the liposomes are clearly visible and do not look jumbled. In a third-party study conducted by a university, CELLg8® Liposomes were the only liposomes that were recognizable and complete.
When we developed the concept for Tespo we needed to find someone who could think outside of the box and problem solve. Once we found Dr. Emek Blair, we accelerated our R&D and launched Tespo in short order. Emek is a responsive, thought-leader that is committed to getting a job done right.
CELLg8® is a registered trademark for a proprietary method in manufacturing custom liposome formulas.
CELLg8 was established in 2010 and expanded in 2015 by Dr. Emek Blair, Ph.D. While studying for his Ph.D. in chemistry at the University of California – Irvine, Dr. Blair discovered a method of creating liposomes that preserved the integrity of the liposome and the nutrient or botanical payload, without the use of solvents, heat, or pressure.
We are cGMP certified specifically for liposome manufacturing by SGS, an International entity that inspects and certifies manufacturing.
We have product stability data for all our Valimenta / CELLg8® products, which in general have an 18-36 month shelf life.
Yes, with the exception of Vitamin D. The starting material for Vitamin D is sheep’s wool lanolin, which is converted into Vitamin D.
We use a trusted, third party vendor for encapsulation and packet filling.
Stay Ahead of the Game with Our Latest Posts
Stay informed about the latest developments at CELLg8®. Keep yourself updated by reading, listening, and watching updates on our technology and current discussions within the liposomal supplement sector. Stay ahead of the game by staying abreast of the most recent advancements and trends in this exciting industry.
