Liposomal Bulk Ingredients & Finished Goods

We offer a wide variety of CELLg8 Liposomal Powders as well as finished goods. For inquiries please contact us here. 

Research and Development

Featured CELLg8® Studies

Liposomal Mineral Absorption

Iron

In a randomized crossover trial, 25 healthy participants ingested either a liposomal multivitamin/mineral or a non-liposomal multivitamin/mineral product. Blood analyses for iron and magnesium were conducted at baseline and every two hours for six hours. Iron levels were significantly increased in the liposomal multi compared with the non-liposomal. Magnesium levels were not significantly different (possible due to the low amount of magnesium in each product). The researchers’ conclusion was that iron absorption from the liposomal multi is significantly enhanced by the liposomal delivery technology.

CELLg8®

Green Tea

A single centre, non-randomised, blind crossover study involving 26 participants . The purpose of the study was to assess the bio-availability of the green tea extract used in the production of CELLg8® Green Tea compared to a standard commercially available extract of green tea commonly found in green tea supplements. Participants consumed 200mg twice per day of a standard green tea extract followed by a 14-day washout period and thereafter 200mg twice per day dose of the extract found in CELLg8® Green Tea was consumed. Blood samples were drawn over a 24-hour period post-consumption to measure levels of catechin concentrations in the blood.

A Pilot Study

Glutathione

A clinical study was undertaken to assess the effect of liposomal glutathione on blood levels and detoxification processes. Seven individuals took a standard glutathione powder, then after a one-week washout took a liposomal glutathione liquid (CELLg8®). Peak blood glutathione was compared, with the liposomal preparation resulting in 22% increase in glutathione levels while the standard glutathione did not change blood glutathione levels.. In another small, open-label study, four healthy individuals took 750 mg of CELLg8®glutathione twice daily for 30 days. Improved detoxification and liver function was demonstrated by decreased bilirubin and 39% decreased mercury.

Liposomal Mineral Absorption

IRON

In a randomized crossover trial, 25 healthy participants ingested either a liposomal multivitamin/mineral or a non-liposomal multivitamin/mineral product. Blood analyses for iron and magnesium were conducted at baseline and every two hours for six hours. Iron levels were significantly increased in the liposomal multi compared with the non-liposomal. Magnesium levels were not significantly different (possible due to the low amount of magnesium in each product). The researchers’ conclusion was that iron absorption from the liposomal multi is significantly enhanced by the liposomal delivery technology.

CELLg8®

Green Tea

A single centre, non-randomised, blind crossover study involving 26 participants . The purpose of the study was to assess the bio-availability of the green tea extract used in the production of CELLg8® Green Tea compared to a standard commercially available extract of green tea commonly found in green tea supplements. Participants consumed 200mg twice per day of a standard green tea extract followed by a 14-day washout period and thereafter 200mg twice per day dose of the extract found in CELLg8® Green Tea was consumed. Blood samples were drawn over a 24-hour period post-consumption to measure levels of catechin concentrations in the blood.

A Pilot Study

Glutathione

A clinical study was undertaken to assess the effect of liposomal glutathione on blood levels and detoxification processes. Seven individuals took a standard glutathione powder, then after a one-week washout took a liposomal glutathione liquid (CELLg8®). Peak blood glutathione was compared, with the liposomal preparation resulting in 22% increase in glutathione levels while the standard glutathione did not change blood glutathione levels.. In another small, open-label study, four healthy individuals took 750 mg of CELLg8®glutathione twice daily for 30 days. Improved detoxification and liver function was demonstrated by decreased bilirubin and 39% decreased mercury.

CELLg8® Powered

Vitamin B12 Study

A single-dose, crossover study was conducted in six human subjects of equivalent doses of two dosage forms of vitamin B12 – a standard liposomal liquid and a liposomal powder-filled capsule (using CELLg8® technology). Each subject was given 3 mg of CELLb12® in one dosage form, followed by a washout period of 14 days, then dosing with the other dosage form.

 

All subjects (with one exception) had an increase above baseline at one or more time points over 135 minutes. Serum B12 increased six-fold on average after taking the CELLb12® liposomal capsule compared to the traditional liposomal liquid when comparing the highest peak of each subject’s serum B12.

CELLg8® Powered

Vitamin C Study

When comparing a “normal” Vitamin C ingestion (dose of 4g) to a Liposomal Vitamin C (also 4g), it’s evident that our CELLg8® Liposomal Delivery System provides much greater circulating Vitamin C concentrations. With increased efficacy, oxidative stress was reduced even during the increased oxidative stress of reperfusion, resulting in meaningful Vitamin C concentration. As CELLg8® has entered the 8th and final generation, our Liposomal Vitamin C had a peak particle size of 8nm, with 92% of the particles being between 60 and 172nm. This tight distribution is indicative of the reproducible and highly controlled manufacturing methodology of CELLg8® Liposomes.

CELLg8®

EGCG

Referred to as epigallocatechin gallate, EGCG is a catechin, which is a kind of plant-based compound. Catechins are further classified into a bigger group of plant compounds known as polyphenols. EGCG and other relevant catechins can protect against cellular destruction brought about by free radicals. Such particles are formed in the body and can harm cells when their numbers soar too high. Eating foods that are rich in catechins can help limit the damage caused by free radicals. 

CELLg8® Powered

Ketones Study

Change in Blood Ketones After Single-Dose Supplementation with Liposomal Ketone Formulation

 

Protocol: Participants ingested a one-time 5-gram dose of a 50:50 liposomal preparation of ketone monoester/1,3-butanediol.

 

Laboratory Analyses: Baseline blood ketone measurement using a ketone meter (KetoCoach meter), then measurements at 15 minutes post-ingestion, 30 minutes post-ingestion, 60 minutes post-ingestion, and a final measurement at 120 minutes.

 

Results: Fifteen minutes after ingesting the liposomal ketone product, all participants had an increase in blood ketones, ranging from 120% to 250% of the baseline level (avg 174%). At 30 minutes post-ingestion, participants’ blood ketones increased from baseline an average of 214%. At 60 minutes, a 66% increase over baseline was seen, and at 120 minutes a 43% increase over baseline was seen. Participants also noted increased mental clarity and acuity.

 

Conclusions: Liposomal ketones are quickly absorbed into the bloodstream, shown by the average level of 174% over baseline at 15 minutes. This continued at 30 minutes when the greatest increase over baseline was seen – an average level of 214%. Blood ketones stayed at levels above baseline at 60 and 120 minutes. This study shows that ingestion of a liposomal ketone product significantly increases blood ketones starting at 15 minutes and continuing for over two hours. With the peak in blood ketones at 30 minutes, it is advisable to ingest this product 15-30 minutes prior to a workout, to maximize energy and workout strength. Exogenous ketones can serve as an alternate energy source that reduces carbohydrate and protein metabolism, while also decreasing fat storage. Ketogenic diets are commonly used to enhance weight loss, mental clarity, exercise performance, and recovery; however, they are cumbersome and difficult for many people to continue long-term due to dietary constraints. Exogenous ketones offer a method of increasing blood ketones quickly without dietary restrictions and may offer a less complicated approach to obtaining the health benefits of ketosis.

 

Summary

  • Ketosis in 20 minutes
  • Increased mental clarity and sharpness
  • Mimics benefits of intermittent fasting
  • Provides effects of a ketogenic diet without the hassle

CELLg8® Powered

Vitamin D Study

The Effect of a Liposomal Cholecalciferol Preparation on 25(OH) Vitamin D Levels – A comparative, open-label study

 

Fifteen healthy participants underwent baseline 25(OH) Vitamin D testing, followed by supplementation with a liposomal product containing 125 mcg (5,000 IU) vitamin D and 400 mcg vitamin K (as MK7) daily for 30 days.  Participants in this study had an average increase in serum 25(OH) Vitamin D of 73% over baseline. (Fig 1) For comparison, the average increase in 25(OH) Vitamin D with supplementation of a non-liposomal preparation for 30 days at this dosage is 16%.

 

Individuals who began the study with a 25(OH) Vitamin D level in the “insufficient” range (below 30 ng/mL) had an even greater response, averaging a 112% increase. (Fig 2)

 

Conclusion: Supplementation with a liposomal vitamin D product for 30 days resulted in a much greater increase in serum 25(OH) Vitamin D than typical results after supplementation with a non-liposomal preparation (avg 73% vs 16%), proving the superior absorption of liposomal Vitamin D.

CELLg8® Powered

Curcumin Study

Three different doses of Liposomal Curcumin were given orally to subjects after metabolic onset. The efficacy of two high doses(0.5mg and 1mg) is obviously better than the 0.25mg dose.

The metabolic function study protocol

  • We have much stricter standards when performing efficacy studies:
    1. Other studies treat subjects as a group despite not all having metabolic slowdown
    2. We consider subjects individually (only subjects with metabolic slowdown were included)
  • Our goal is to make sure the efficacy could be clinically translational
  • Below is the second study we have performed with Liposomal Curcumin

Conclusion

  • Liposomal Curcumin was shown to rebound metabolic function in subjects.

CELLg8® Powered

Sleep Study

CELLg8® Sleep is designed to reduce the time it takes to fall asleep, lengthen the duration of sleep, and provide renewed vitality after waking up in the morning, with only half of the recommended dosage of a standard supplement. This can also result in fewer instances of waking up during the night.

DESIGN:
8 Participants
Single-blind study comparing CELLg8® SLEEP product vs. placebo
Each participant took one product for 7 days, then crossed over to the other product

RESULTS:
Placebo did not improve sleep in any subject
When taking the SLEEP product, duration of sleep increased in 50 percent (n=4) by an average of 9-percent., decreased in 37 percent (n=3), and stayed the same in one.
Three of the four who felt no difference between the two products were experiencing chronic pain (none of the other subjects had chronic pain), which may have confounded the results.
Seventy-five percent of subjects in the treatment group had a significant decrease in the number of times awakened, averaging a 50-percent improvement in awakenings.
Seventy-five percent of subjects preferred the SLEEP product over the placebo.

CELLg8® Powered

Vitamin B12 Study

A single-dose, crossover study was conducted in six human subjects of equivalent doses of two dosage forms of vitamin B12 – a standard liposomal liquid and a liposomal powder-filled capsule (using CELLg8® technology). Each subject was given 3 mg of CELLb12® in one dosage form, followed by a washout period of 14 days, then dosing with the other dosage form.

 

All subjects (with one exception) had an increase above baseline at one or more time points over 135 minutes. Serum B12 increased six-fold on average after taking the CELLb12® liposomal capsule compared to the traditional liposomal liquid when comparing the highest peak of each subject’s serum B12.

CELLg8® Powered

Vitamin C Study

When comparing a “normal” Vitamin C ingestion (dose of 4g) to a Liposomal Vitamin C (also 4g), it’s evident that our CELLg8® Liposomal Delivery System provides much greater circulating Vitamin C concentrations. With increased efficacy, oxidative stress was reduced even during the increased oxidative stress of reperfusion, resulting in meaningful Vitamin C concentration. As CELLg8® has entered the 8th and final generation, our Liposomal Vitamin C had a peak particle size of 8nm, with 92% of the particles being between 60 and 172nm. This tight distribution is indicative of the reproducible and highly controlled manufacturing methodology of CELLg8® Liposomes.

CELLg8®

EGCG

Referred to as epigallocatechin gallate, EGCG is a catechin, which is a kind of plant-based compound. Catechins are further classified into a bigger group of plant compounds known as polyphenols. EGCG and other relevant catechins can protect against cellular destruction brought about by free radicals. Such particles are formed in the body and can harm cells when their numbers soar too high. Eating foods that are rich in catechins can help limit the damage caused by free radicals. 

CELLg8® Powered

Ketones Study

Change in Blood Ketones After Single-Dose Supplementation with Liposomal Ketone Formulation

 

Protocol: Participants ingested a one-time 5-gram dose of a 50:50 liposomal preparation of ketone monoester/1,3-butanediol.

 

Laboratory Analyses: Baseline blood ketone measurement using a ketone meter (KetoCoach meter), then measurements at 15 minutes post-ingestion, 30 minutes post-ingestion, 60 minutes post-ingestion, and a final measurement at 120 minutes.

 

Results: Fifteen minutes after ingesting the liposomal ketone product, all participants had an increase in blood ketones, ranging from 120% to 250% of the baseline level (avg 174%). At 30 minutes post-ingestion, participants’ blood ketones increased from baseline an average of 214%. At 60 minutes, a 66% increase over baseline was seen, and at 120 minutes a 43% increase over baseline was seen. Participants also noted increased mental clarity and acuity.

 

Conclusions: Liposomal ketones are quickly absorbed into the bloodstream, shown by the average level of 174% over baseline at 15 minutes. This continued at 30 minutes when the greatest increase over baseline was seen – an average level of 214%. Blood ketones stayed at levels above baseline at 60 and 120 minutes. This study shows that ingestion of a liposomal ketone product significantly increases blood ketones starting at 15 minutes and continuing for over two hours. With the peak in blood ketones at 30 minutes, it is advisable to ingest this product 15-30 minutes prior to a workout, to maximize energy and workout strength. Exogenous ketones can serve as an alternate energy source that reduces carbohydrate and protein metabolism, while also decreasing fat storage. Ketogenic diets are commonly used to enhance weight loss, mental clarity, exercise performance, and recovery; however, they are cumbersome and difficult for many people to continue long-term due to dietary constraints. Exogenous ketones offer a method of increasing blood ketones quickly without dietary restrictions and may offer a less complicated approach to obtaining the health benefits of ketosis.

 

Summary

  • Ketosis in 20 minutes
  • Increased mental clarity and sharpness
  • Mimics benefits of intermittent fasting
  • Provides effects of a ketogenic diet without the hassle

CELLg8® Powered

Vitamin D Study

The Effect of a Liposomal Cholecalciferol Preparation on 25(OH) Vitamin D Levels – A comparative, open-label study

 

Fifteen healthy participants underwent baseline 25(OH) Vitamin D testing, followed by supplementation with a liposomal product containing 125 mcg (5,000 IU) vitamin D and 400 mcg vitamin K (as MK7) daily for 30 days.  Participants in this study had an average increase in serum 25(OH) Vitamin D of 73% over baseline. (Fig 1) For comparison, the average increase in 25(OH) Vitamin D with supplementation of a non-liposomal preparation for 30 days at this dosage is 16%.

 

Individuals who began the study with a 25(OH) Vitamin D level in the “insufficient” range (below 30 ng/mL) had an even greater response, averaging a 112% increase. (Fig 2)

 

Conclusion: Supplementation with a liposomal vitamin D product for 30 days resulted in a much greater increase in serum 25(OH) Vitamin D than typical results after supplementation with a non-liposomal preparation (avg 73% vs 16%), proving the superior absorption of liposomal Vitamin D.

CELLg8® Powered

Curcumin Study

Three different doses of Liposomal Curcumin were given orally to subjects after metabolic onset. The efficacy of two high doses(0.5mg and 1mg) is obviously better than the 0.25mg dose.

The metabolic function study protocol

  • We have much stricter standards when performing efficacy studies:
    1. Other studies treat subjects as a group despite not all having metabolic slowdown
    2. We consider subjects individually (only subjects with metabolic slowdown were included)
  • Our goal is to make sure the efficacy could be clinically translational
  • Below is the second study we have performed with Liposomal Curcumin

Conclusion

  • Liposomal Curcumin was shown to rebound metabolic function in subjects.

CELLg8® Powered

Sleep Study

CELLg8® Sleep is designed to reduce the time it takes to fall asleep, lengthen the duration of sleep, and provide renewed vitality after waking up in the morning, with only half of the recommended dosage of a standard supplement. This can also result in fewer instances of waking up during the night.

DESIGN:
8 Participants
Single-blind study comparing CELLg8® SLEEP product vs. placebo
Each participant took one product for 7 days, then crossed over to the other product

RESULTS:
Placebo did not improve sleep in any subject
When taking the SLEEP product, duration of sleep increased in 50 percent (n=4) by an average of 9-percent., decreased in 37 percent (n=3), and stayed the same in one.
Three of the four who felt no difference between the two products were experiencing chronic pain (none of the other subjects had chronic pain), which may have confounded the results.
Seventy-five percent of subjects in the treatment group had a significant decrease in the number of times awakened, averaging a 50-percent improvement in awakenings.
Seventy-five percent of subjects preferred the SLEEP product over the placebo.

CELLg8® Research

Understanding CELLg8® Liposomes

CELLg8® has developed industry-leading liposomal technology over the last 20+ years. At this time, CELLg8® has been through 8 generations and is now in its final iteration. CELLg8® Liposomes have been clinically proven to have better absorption, increased efficacy, and no side effects. We currently have multiple ongoing studies to further prove the effectiveness and safety of CELLg8® Technology. 

Stomachs will vaporize more nutrients than they absorb. Humans are only able to absorb a tiny percentage (typically 1-5%) of nutrients in vitamins and other ingredients. When these ingredients are encapsulated within liposomes, our bodies can absorb up to 15 times more nutrients because we won’t reject the liposomes. Liposomes are the future of supplements.

What Makes CELLg8® Different

Science has our back

From the founding of our company, we have always made it a goal to provide proof to our clients and consumers that the products we make don't just work incredibly well, they are also very safe to use. At CELLg8®, we use significant resources in researching, conducting, and publishing clinical studies to prove the efficacy of our technology.

Liposome Manufacturing

Our process from start to finish is gentle on the ingredients to optimize shelf life. We don't use heat, pressure, or chemicals to produce CELLg8® liposomes.

CELLg8® is scaleable

CELLg8® Liposomes can be produced at an industry leading rate, allowing for mass production on multiple products. Our manufacturing facilities are able to produce from 10,000 to 50,000 bottles as finished products per day. We can also produce over 10,000 kg of bulk material per day.

Custom Formulations

Bulk CELLg8® Powders

Clinically backed with published studies!

Choose from a wide array of stock in 25 kg boxes or create your own custom formulas with our doctors.

Learn More

CEllg8® Liquids

Finished Goods or Bulk - We carry a wide variety of stock, ready to sell products for white label of or create your own custom products with custom packaging and formulas.

Learn More

CELLg8® Capsules & Softgels

Choose from a wide array of stock capsules ready to sell on a store shelf or create your own custom formulas with custom packaging of your choice.

Learn More
Standalone or Combination Ingredients

Melatonin
N-Acetylcysteine
Resveratrol
Rhodiola Rosea
Shiitake Mushroom
Zeaxanthin
Phosphatidylcholine
Linoleic Acid
Oleic Acid

Vitamin B Series
Vitamin C Series
Vitamin D
Vitamin K
Chromium
Selenium
Acai Berry
Astaxanthin
Astragalus
Bacopa

Curcumin
GABA
Ginger Root
Ginkgo
Glutathione
Green Tea
Guarana
Hesperidin
Huperzine A
Maca Root

See a CELLg8® Liposome in Action

Transmission Electron Microscope

See CELLg8 liposomes pictured under a TEM to the left. Here you can see the full encapsulation of the nutrient within the liposome. When viewing a liposome under a TEM, it's important that the liposomes are clearly visible and do not look jumbled. In a third-party study conducted by a university, CELLg8® Liposomes were the only liposomes that were recognizable and complete.

Collaborations
CELLg8® FAQ

CELLg8® is a registered trademark for a proprietary method in manufacturing custom liposome formulas.

CELLg8 was established in 2010 and expanded in 2015 by Dr. Emek Blair, Ph.D. While studying for his Ph.D. in chemistry at the University of California – Irvine, Dr. Blair discovered a method of creating liposomes that preserved the integrity of the liposome and the nutrient or botanical payload, without the use of solvents, heat, or pressure.

We are cGMP certified specifically for liposome manufacturing by SGS, an International entity that inspects and certifies manufacturing.

We have product stability data for all our Valimenta / CELLg8® products, which in general have an 18-36 month shelf life.

Yes, with the exception of Vitamin D. The starting material for Vitamin D is sheep’s wool lanolin, which is converted into Vitamin D.

We use a trusted, third party vendor for encapsulation and packet filling.