Vitamin B12 Study


A single-dose, crossover study was conducted in six human subjects of equivalent doses of two dosage forms of vitamin B12 – a standard liposomal liquid and a liposomal powder-filled capsule (using CELLg8® technology). Each subject was given 3 mg of CELLb12® in one dosage form, followed by a washout period of 14 days, then dosing with the other dosage form.

All subjects (with one exception) had an increase above baseline at one or more time points over 135 minutes. Serum B12 increased six-fold on average after taking the CELLb12® liposomal capsule compared to the traditional liposomal liquid when comparing the highest peak of each subject’s serum B12.