The Importance of Folate: Understanding the Critical Role of Vitamin B9 in Methylation

AuthorEmek Blair Ph.D.Published OnFebruary 3, 2023

Folate, also known as vitamin B9, is an essential nutrient that plays a critical role in methylation biochemistry. Folate is required for the methylation cycle, the process by which methyl groups are added to molecules such as DNA, RNA, and proteins, it is a process that affects the expression of genes and can play a role in correct DNA translation.

Folate is required for the formation of S-adenosylmethionine (SAM), which is the main methyl donor in the cell. SAM is used in many methylation reactions, including the methylation of DNA and proteins.

Folate deficiency can lead to disruptions in the methylation cycle, leading to changes in the expression of genes that are involved in critical biochemical steps. Adequate intake of folate is important for maintaining normal DNA methylation and proper gene expression.

References

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354546/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879467/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7163664/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997693/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354546/

Emek Blair Ph.D.

Dr. Blair has formulated upwards of 100 unique liposomal formulas that have successfully been brought to market by some of the largest brands in the world. Several of Dr. Blair’s formulas have been internationally recognized and awarded by the science and supplement industries. Dr. Blair continues to perform clinical trials with various high-impact medical doctors around the world; this research shows how natural products, when properly delivered, are critical to maximizing health.

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