Camellia Sinesis, commonly known as green tea, is the oldest herbal tea known to humans. It was first brewed in China in 2737 BC. Today green tea is consumed around the world by millions of people who enjoy it for various health benefits. Accepted benefits include vitality, detoxification, mental focus, and weight management. Green tea has a long history as a supportive aid in conditions such as cancer, diabetes, and cardiovascular health. Thousands of clinical studies have been conducted and published investigating the various health benefits of green tea.
Scientific research has shown that green tea contains a number of bioactive compounds. The major benefit of green tea steam from its rich supply of catechins, of which eight types are found in green tea. Catechins are regarded as the most powerful polyphenols providing the brain and body with strong antioxidant protection. Catechins were first isolated from green tea in 1929 by Michiyo Tsujimura, a Japanese agricultural scientist and biochemist. Her research focused on the components of the green team and she was the first woman in Japan to receive a doctoral degree in agriculture.
Catechins are effective scavengers of reactive oxygen species and may also function indirectly as antioxidants through their effects on transcription factors and enzyme activities. Catechins support the body’s major detox organ, the liver, improving liver function and reversing declines in antioxidant defenses. Studies also indicate catechins have the ability to block the amount of fat stored in the liver which is of particular interest due to high levels of non-alcoholic fatty liver disease (NAFLD).
Due to catechins’ ability to target multiple anti-inflammatory signaling pathways, a single pathway cannot be assigned. The major catechin epigallocatechin gallate (EGCG) has been noted to decrease NK-kB activity, regarded as the master switch to inflammation.
Catechins may alter brain aging processes and serve as possible neuroprotective agents in progressive neurodegenerative disorders such as Parkinson’s and Alzheimer’s disease.
Studies show that green tea can improve insulin sensitivity, decreasing fasting glucose levels as well as fasting insulin concentration.
Green tea has been shown to positively impact the major risk factors associated with cardiovascular disease, lowering LDL cholesterol and protecting LDL particles from oxidation. Observational studies indicate that people consuming green tea reduce their risk of cardiovascular disease by 31%.
The traditional and widely accepted method of consuming green tea is brewing the leave sand consuming it as a drink. However, there are limitations to this method when wanting to obtain the maximum health benefits of green tea or when green tea is used as a supportive aid during the treatment of an illness.
The quality and level of catechins found in green tea varies from plant to plant. Drinking a tea with very low levels of catechins will be of little benefit, therefor standardization is required.
Heavy metals have been found in a number of commercial brands grown near industrial areas. We need to question if the tea is free of agrochemicals and containments. This is especially important when a large quantity of tea is being consumed on a daily basis.
For sufficient benefit multiple cups of tea per day need to be consumed on a consistent, day to day basis.
Those sensitive to caffeine and the stimulating effect of green tea may find it impossible to consume the required volume of green tea on an ongoing basis.
Absorption of catechins from the green tea may not be optimal, especially in those with compromised digestive systems and overall health.
Once the benefits of green tea become known, the challenge of consuming adequate amounts of high quality green tea throughout the day emerged, giving rise to the development of supplements. A quality supplement can offer the benefits of green tea conveniently.
Companies have focused on producing high concentration supplements which deliver in rich supply of catechins in a serving. Very little thought was given to bio-availability and absorption. We know today it is not what you consume but what you absorb that is the most important factor. We need to then ensure that absorption is achieved in a safe and healthy manner.
A person may consume a desired therapeutic amount of substance but if absorption is limited then the result itself is limited, and there is a greater potential for negative side effects such as gastrointestinal upset. Negative side effects lead to non-compliance and potentially discontinuation.
A group of scientists and medical experts working with the latest extraction and absorption technology with a keen interest in food and natural substances focused their energy on green tea.
Due to the vast health benefits green tea offers and their understanding that these benefits are limited by the quality of tea as well as absorption of regular supplementation, they sought to develop a new green tea extract which could overcome the current challenges.
After years of research, development and collaboration and combining the best of nature with science, the final result is Origine 8™ which is a true breakthrough in not only green tea supplementation but in health.
A single centre, non-randomised, blind crossover study involving 26 participants was conducted by the PCDDP at the North-West University in South Africa. The purpose of the study was to assess the bio-availability of the green tea extract used in the production of Origine 8™ compared to a standard commercially available extract of green tea commonly found in green tea supplements
Participants consumed 200mg twice per day of a standard green tea extract followed by a 14-day washout period and thereafter 200mg twice per day dose of the extract found in Origine 8™ was consumed. Blood samples were drawn over a 24-hour period post-consumption to measure levels of catechin concentrations in the blood.
A complication of the concentration-time curves (AUC) as determined by LC-MS-MS was possible for levels of epigallocatechin, epicatechin, epigallocatechin, gallate, epicatechin gallate, catechin gallate, gallocatechin, and total catechin in the plasma. This allowed for comparative statistical endpoints including time at a maximum concentration (Tmax) and maximum concentration (Cmax) for plasma concentrations of individual and total catechins
Origine 8™ delivered an average concentration of catechins of 11,630 ng/ml compared to a concentration of 930 ng/ml delivered by the standard green tea extract. A 12-fold greater average concentration was delivered by Origine 8™. Origine 8™ offered complete absorption of all 8 catechins found in green tea. With the exception of EGCG standard green tea extract provided insignificant levels of the other 7 catechins in comparison to Origine 8™ as demonstrated in figure 1.
The average concentration of Epigallocatechin Gallate (EGCG) delivered by Origine 8™ was 6120 ng/ml compared to an average concentration of 612 ng/mlEGCG delivered by the standard green tea extract. EGCG is regarded as key catechin and Origine 8™ delivers a 10-fold greater total concentration.
Origine 8™ resulted in a far greater half-life compared to the standard green tea extract. Catechins delivered by Origine 8™ were still found to be present in the plasma after 24 hours whereas standard green tea was cleared from the body after only 6 hours. This means that Origine 8™ could be used as a once-per-day dose whilst standard green tea would require multiple doses of far greater size throughout the day to deliver the same levels of catechins achieved through a single dose of the far small size of Origine 8™.
T-Intestinal uptake (bioavailability) of generic green tea catechins is normally low, ranging from 1.68% in humans, similar in rats, and up to 13-26.5% in mice.
CELLg8 catechin complex absorption is further greatly enhanced through CELLg8 science delivering a synergistic complex of all eight catechins mainly the cis isomer from which the body naturally transports the catechins from the gut to the plasma. Plandai’s proprietary extraction technology takes live plant material and unzips the molecules, releasing the phytonutrients in an active, bioavailable, and stable form. Demonstrated effective from human clinical trails and research.
CELLg8 selected green tea catechins as the first plant of choice in which to apply its technology. The resulting extract has been named CELLg8 Catechin Complex. The green tea used in the extract is grown in the Nilgiris Ooty area in India with a subtropical climate at 8000 feet above sea level.
CELLg8 Catechin Complex offers a breakthrough green tea extract both in quality, and efficiency, demonstrated by clinical evidence and manufactured in a world class and one of a kind production facility. This is why it was the obvious choice for us when developing Origine 8™
Liposomes are tiny nano-sized bubbles with an outer shell comprised of healthy lipids and a hollow aqueous center that can be filled with a variety of substances. We have long postulated that the other layer of the Liposome protects a substance from gastric juices and liver enzymes; now, clinical studies are showing that Liposomes support the absorption of nutrition and have excellent efficacy. Liposomes work by initially protecting the payload from the harsh acidic environment of the stomach. Once past the stomach, the payload is delivered where needed by absorption through one of the many mechanisms available to liposomes. This higher absorption of nutrition allows its full benefit to be realized. An added advantage of liposomes is increased circulation time of the payload, which allows for a longer active life and benefit.
Origine 8™ uses the only known GMP and registered Liposome manufacturing facility in the world. In the case of the liposome used in the production of Origine 8, phosphatidylcholine is used and extracted from non-GMO sunflower, the liposome itself has the added benefit of becoming nutrition for the liver, brain, mitochondria, eyes, and most essential cells int he human body.
of entrapped molecules
of molecules from gastro-intestinal tract
of labile molecules from degradation of early metabolism
of distribution and circulatory half-life molecules in the body
Liposome consists of biomaterial that is generally regarded as safe; no synthetic compounds are used in the production of Liposome.
Liposome uses no sugar, gluten, or artificial additives and is GMO-free.
The manufacturing process is environmentally-friendly, using no harsh chemicals nor does it contaminate water.
Organically grown green tea is sourced from the Nilgries Ooty region of India
The proprietary extraction process produces a natural extract with optimal levels of all 8 bioactive catechins
Our organic green tea extract is then flown to Valimenta in the US where it is enhanced with patented CELLg8 technology which enhances bio-availability and active life and stabilizes the catechins from degradation.
The final product is bottled and packaged in our GMP facility.
Ounce tested and manufactured, Origine 8™ is finished and ready for consumption.
Consume 1 capsule in the morning. It is suggested whilst using Origine 8™ that one increases water intake. Do not consume more than 1 capsule in a 24-hour period.
Pregnancy and breastfeeding. Bleeding disorders and those using anti-coagulation medication such as Warfarin. A potential detoxification effect may be experienced which will vary from person to person. This will be a temporary process, which may last a few hours from first taking Origine 8™ up to several days. While this may cause discomfort, it must be noted that it is in fact a positive and necessary process. Origine 8™ contains only 11mg of caffeine per capsule, but this low level may still be stimulatory to those sensitive to caffeine.
30 clear vegetable capsules containing green powdered-like extract packed in a glass jar.
Use within 90 days of opening. Store in a cool, dry environment and avoid exposure to light.
Origine 8™ is a first-of-its-kind green tea supplement based on a patented extract that when compared to regular green tea extracts, provides a 12 times greater absorption, sustains in the body for up to 24 hours versus 6 hours, and for the first time offers a complete absorption of all eight of green tea’s catechins. This has been verified through human clinical studies conducted at the prestigious department of pharmacology at the university of North West in South Africa. All of this is in the convenience of a single capsule per day. The first and only green tea extract to offer complete catechin absorption.